zuclopenthixol-7356 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the zuclopenthixol-7356 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AIM1L absent in melanoma 1-like
AKR1C1 aldo-keto reductase family 1, member C1
APC adenomatous polyposis coli
AQP3 aquaporin 3 (Gill blood group)
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ASCL1 achaete-scute family bHLH transcription factor 1
ATAT1 alpha tubulin acetyltransferase 1
ATF3 activating transcription factor 3
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCNG2 cyclin G2
CD6 CD6 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEMIP cell migration inducing protein, hyaluronan binding
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNOT4 CCR4-NOT transcription complex, subunit 4
DCTN1 dynactin 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DSCAM Down syndrome cell adhesion molecule
DUSP4 dual specificity phosphatase 4
DVL2 dishevelled segment polarity protein 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGFR epidermal growth factor receptor
ELOVL5 ELOVL fatty acid elongase 5
ERCC2 excision repair cross-complementation group 2
ETV5 ets variant 5
FAM169A family with sequence similarity 169, member A
FAM189A2 family with sequence similarity 189, member A2
FBXO21 F-box protein 21
FLJ42627 uncharacterized LOC645644
FN1 fibronectin 1
GBP1 guanylate binding protein 1, interferon-inducible
GSTP1 glutathione S-transferase pi 1
HIC2 hypermethylated in cancer 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ICAM1 intercellular adhesion molecule 1
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INSIG1 insulin induced gene 1
IRF9 interferon regulatory factor 9
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUN jun proto-oncogene
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA3 melanoma antigen family A3
MFGE8 milk fat globule-EGF factor 8 protein
MYOF myoferlin
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OSGIN1 oxidative stress induced growth inhibitor 1
PAX2 paired box 2
PDE4DIP phosphodiesterase 4D interacting protein
PDE8B phosphodiesterase 8B
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPAP2B phosphatidic acid phosphatase type 2B
PRSS53 protease, serine, 53
RECQL5 RecQ protein-like 5
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
RPGRIP1L RPGRIP1-like
S100A11 S100 calcium binding protein A11
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX9 SRY (sex determining region Y)-box 9
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SRCAP Snf2-related CREBBP activator protein
STX5 syntaxin 5
TGFB1 transforming growth factor, beta 1
THBS3 thrombospondin 3
TLK1 tousled-like kinase 1
TMEM212 transmembrane protein 212
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM2 tripartite motif containing 2
TRIM29 tripartite motif containing 29
TROVE2 TROVE domain family, member 2
TSC22D3 TSC22 domain family, member 3
UBXN6 UBX domain protein 6
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZFX zinc finger protein, X-linked
ZNF821 zinc finger protein 821
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAP2 ArfGAP with dual PH domains 2
ADGRE5 adhesion G protein-coupled receptor E5
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
AXIN1 axin 1
BACE1 beta-site APP-cleaving enzyme 1
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
C10ORF95 chromosome 10 open reading frame 95
C22ORF29 chromosome 22 open reading frame 29
C9ORF3 chromosome 9 open reading frame 3
CASZ1 castor zinc finger 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC69 coiled-coil domain containing 69
CCNE1 cyclin E1
CD82 CD82 molecule
CHRM3 cholinergic receptor, muscarinic 3
COG4 component of oligomeric golgi complex 4
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CUL9 cullin 9
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNALI1 dynein, axonemal, light intermediate chain 1
DUSP13 dual specificity phosphatase 13
ELSPBP1 epididymal sperm binding protein 1
FAM110B family with sequence similarity 110, member B
FBXO22 F-box protein 22
FRS2 fibroblast growth factor receptor substrate 2
GAA glucosidase, alpha; acid
GAREM GRB2 associated, regulator of MAPK1
GDAP1 ganglioside induced differentiation associated protein 1
GHR growth hormone receptor
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H1E histone cluster 1, H1e
HIST1H4D histone cluster 1, H4d
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNAR1 interferon (alpha, beta and omega) receptor 1
KIF13B kinesin family member 13B
KLHL25 kelch-like family member 25
KLK5 kallikrein-related peptidase 5
LOC730101 uncharacterized LOC730101
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MATK megakaryocyte-associated tyrosine kinase
MBTPS2 membrane-bound transcription factor peptidase, site 2
MITF microphthalmia-associated transcription factor
MYBBP1A MYB binding protein (P160) 1a
NEO1 neogenin 1
NPFFR1 neuropeptide FF receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY1R neuropeptide Y receptor Y1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDZRN3 PDZ domain containing ring finger 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPT2 palmitoyl-protein thioesterase 2
PRR15L proline rich 15-like
RANBP17 RAN binding protein 17
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF25 ring finger protein 25
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
SCHIP1 schwannomin interacting protein 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIX1 SIX homeobox 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SOBP sine oculis binding protein homolog (Drosophila)
SP1 Sp1 transcription factor
SPAG7 sperm associated antigen 7
SREK1IP1 SREK1-interacting protein 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBX19 T-box 19
TESPA1 thymocyte expressed, positive selection associated 1
TGFB3 transforming growth factor, beta 3
THOP1 thimet oligopeptidase 1
TMEM53 transmembrane protein 53
TUBG2 tubulin, gamma 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXNL4B thioredoxin-like 4B
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
ZNF219 zinc finger protein 219
ZNF318 zinc finger protein 318
ZNF428 zinc finger protein 428
ZNF506 zinc finger protein 506
ZNF606 zinc finger protein 606
ZSCAN26 zinc finger and SCAN domain containing 26