Name | Apoptosis-enhancing nuclease |
Description | Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis. |
UniProt ID | Q8WTP8 |
Gene | AEN |