AEN_HUMAN Protein

Name Apoptosis-enhancing nuclease
Description Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.
UniProt ID Q8WTP8
Gene AEN