ARHG8_HUMAN Protein

Name Neuroepithelial cell-transforming gene 1 protein
Description Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
UniProt ID Q7Z628
Gene NET1