Name | Rho guanine nucleotide exchange factor 26 |
Description | Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry. |
UniProt ID | Q96DR7 |
Gene | ARHGEF26 |