DEN1A_HUMAN Protein

Name DENN domain-containing protein 1A
Description Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles.
UniProt ID Q8TEH3
Gene DENND1A