| Name | Eukaryotic translation initiation factor 2-alpha kinase 3 |
| Description | Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function (By similarity). |
| UniProt ID | Q9NZJ5 |
| Gene | EIF2AK3 |
