ERAP2_HUMAN Protein

Name Endoplasmic reticulum aminopeptidase 2
Description Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
UniProt ID Q6P179
Gene ERAP2