FGD5_HUMAN Protein

Name FYVE, RhoGEF and PH domain-containing protein 5
Description Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.
UniProt ID Q6ZNL6
Gene FGD5