FXL12_HUMAN Protein

Name F-box/LRR-repeat protein 12
Description Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia.
UniProt ID Q9NXK8
Gene FBXL12