| Name | Pyrin and HIN domain-containing protein 1 |
| Description | Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. |
| UniProt ID | Q6K0P9 |
| Gene | PYHIN1 |
