LIRA3_HUMAN Protein

Name Leukocyte immunoglobulin-like receptor subfamily A member 3
Description Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
UniProt ID Q8N6C8
Gene LILRA3