MARH8_HUMAN Protein

Name E3 ubiquitin-protein ligase MARCH8
Description E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.
UniProt ID Q5T0T0
Gene MARCH8