Name | E3 ubiquitin-protein ligase MIB2 |
Description | E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity). |
UniProt ID | Q96AX9 |
Gene | MIB2 |