MIB2_HUMAN Protein

Name E3 ubiquitin-protein ligase MIB2
Description E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).
UniProt ID Q96AX9
Gene MIB2