MICA3_HUMAN Protein

Name Protein-methionine sulfoxide oxidase MICAL3
Description Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Involved in exocytic vesicles tethering and fusion: the monooxygenase activity is required for this process.
UniProt ID Q7RTP6
Gene MICAL3