| Name | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 |
| Description | Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity. |
| UniProt ID | O95803 |
| Gene | NDST3 |
