P4R3A_HUMAN Protein

Name Serine/threonine-protein phosphatase 4 regulatory subunit 3A
Description Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
UniProt ID Q6IN85
Gene SMEK1