| Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 |
| Description | Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. |
| UniProt ID | Q8N3E9 |
| Gene | PLCD3 |
