| Name | E3 ubiquitin-protein ligase RNF185 |
| Description | E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2. |
| UniProt ID | Q96GF1 |
| Gene | RNF185 |