| Name | Rap guanine nucleotide exchange factor 1 |
| Description | Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth. |
| UniProt ID | Q13905 |
| Gene | RAPGEF1 |
