| Name | SUMO-activating enzyme subunit 1 |
| Description | The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. |
| UniProt ID | Q9UBE0 |
| Gene | SAE1 |
