| Name | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 |
| Description | Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling. |
| UniProt ID | Q9Y3Z3 |
| Gene | SAMHD1 |
