SAS6_HUMAN Protein

Name Spindle assembly abnormal protein 6 homolog
Description Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers.
UniProt ID Q6UVJ0
Gene SASS6