Name | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 |
Description | Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B (By similarity). Required for DUX4 silencing in somatic cells. |
UniProt ID | A6NHR9 |
Gene | SMCHD1 |