SMHD1_HUMAN Protein

Name Structural maintenance of chromosomes flexible hinge domain-containing protein 1
Description Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B (By similarity). Required for DUX4 silencing in somatic cells.
UniProt ID A6NHR9
Gene SMCHD1