TF2H2_HUMAN Protein

Name General transcription factor IIH subunit 2
Description Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.
UniProt ID Q13888
Gene GTF2H2