Name | T-lymphoma invasion and metastasis-inducing protein 1 |
Description | Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration. |
UniProt ID | Q13009 |
Gene | TIAM1 |