Gene Expression Omnibus Resource

Description	The Gene Expression Omnibus is a database of functional genomic data obtained by microarray or next generation sequencing. GEO can be mined for studies that measured gene expression profiles of cells or tissues in control and experimental conditions, where the experimental condition may be a disease, pharmacologic perturbation or genetic perturbation (over-expression, mutation, knockdown or knockout).
Citation(s)	Barrett, T et al. (2013) NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 41:D991-5. Dudley, JT et al. (2009) Disease signatures are robust across tissues and experiments. Mol Syst Biol. 5:307. Edgar, R et al. (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 30:207-10.
Acronym	GEO
External Link	https://www.ncbi.nlm.nih.gov/geo/

Datasets

Dataset	Description	Category	Attribute	Views
Signatures of Differentially Expressed Genes for Diseases	mRNA expression profiles for cell lines or tissues following disease perturbation	transcriptomics	disease perturbation	6910
Signatures of Differentially Expressed Genes for Gene Perturbations	mRNA expression profiles for cell lines or tissues following genetic perturbation (knockdown, knockout, over-expression, mutation)	transcriptomics	gene perturbation	3565
Signatures of Differentially Expressed Genes for Kinase Perturbations	mRNA expression profiles for cell lines or tissues following kinase perturbation (inhibition, activation, knockdown, knockout, over-expression, mutation)	transcriptomics	kinase perturbation	4091
Signatures of Differentially Expressed Genes for Small Molecules	mRNA expression profiles for cell lines or tissues following small molecule perturbation	transcriptomics	small molecule perturbation	2905
Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	mRNA expression profiles for cell lines or tissues following transcription factor perturbation (inhibition, activation, knockdown, knockout, over-expression, mutation)	transcriptomics	transcription factor perturbation	4269
Signatures of Differentially Expressed Genes for Viral Infections	mRNA expression profiles for cell lines or tissues following viral infection	transcriptomics	virus perturbation	3825