Genotype Tissue Expression Resource

Description	The Genotype-Tissue Expression project is a genome mapping project that seeks to discover expression quantitative trait loci in the human genome. Expression quantitative trait loci (eQTL) are regions of the genome where DNA sequence variation is correlated with variation of expression of a gene or set of genes. The GTEx Project discovers eQTL by profiling SNPs and gene expression in many human tissue samples and testing for statistically significant associations between SNPs and differentially expressed genes.
Citation(s)	GTEx, Consortium et al. (2015) Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science. 348:648-60. GTEx, Consortium et al. (2013) The Genotype-Tissue Expression (GTEx) project. Nat Genet. 45:580-5. GTEx Consortium, et al. (2020) The GTEx Consortium atlas of genetic regulatory effects across human tissues. Science. 369:1318-30.
Acronym	GTEx
External Link	https://gtexportal.org/home/

Datasets

Dataset	Description	Category	Attribute	Views
eQTL	Significance values for all gene-SNP pairs testing likelihood that SNP affects gene expression	genomics	SNP	7584
Tissue Gene Expression Profiles	Gene expression profiles for tissues from GTEx by RNA-seq	transcriptomics	tissue	16695
Tissue Sample Gene Expression Profiles	RNA-seq gene expression profiles for tissue samples from GTEx	transcriptomics	tissue sample	11461
Tissue Gene Expression Profiles 2023	Gene expression profiles for tissues from GTEx by RNA-seq	transcriptomics	tissue	774
Tissue-Specific Aging Signatures	Tissue-specific aging signatures createed from GTEx RNA-seq gene expression profiles	transcriptomics	tissue sample	1283
eQTL 2025	Significance values for all gene-SNP pairs testing likelihood that SNP affects gene expression	genomics	SNP	7559