Kinase Enrichment Analysis Resource

Description Kinase Enrichment Analysis (KEA) is a gene-set enrichment analysis tool tailored to test if query gene-sets are enriched with genes known to interact with kinases. KEA utilizes a gene-set library with kinases labeling sets of interacting proteins. Many of the interacting proteins are known substrates of the kinases, and many of the kinase-substrate interactions are annotated with phosphosite-level detail (the specific phosphorylated amino acid residue(s) are indicated). Kinase-substrate interactions in KEA were obtained by curation of biomedical literature and integrated with other databases of kinase-substrate interactions, such as Phospho.ELM (Dinkel, Nucleic Acids Research, 2011) and PhosphoSitePlus (Hornbeck, Nucleic Acids Research, 2012).
Acronym KEA
External Link


Dataset Description Category Attribute Views
Substrates of Kinases protein substrates of kinases from published low-throughput and high-throughput phosphoproteomics studies physical interactions kinase 3887