Replogle et al., Cell, 2022 Resource

Description Data from genome-scale Perturb-seq experiments using CRISPRi to target all expressed genes in K562 chronic myeloid leukemia cells and all DepMap essential genes in RPE1 retinal pigment epithelial cells
Citation(s)
External Link https://gwps.wi.mit.edu/

Datasets

Dataset Description Category Attribute Views
K562 Genome-wide Perturb-seq Gene Perturbation Signatures Gene expression profiles in the K562 cell line following CRISPRi genetic perturbation transcriptomics gene perturbation 5622
K562 Essential Perturb-seq Gene Perturbation Signatures Gene expression profiles in the K562 cell line following CRISPRi genetic perturbation of essential genes transcriptomics gene perturbation 7413
RPE1 Essential Perturb-seq Gene Perturbation Signatures Gene expression profiles in the RPE1 cell line following CRISPRi genetic perturbation of essential genes transcriptomics gene perturbation 5225