Name

NBEA Gene

neurobeachin

This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]

NBEAP1 Gene

neurobeachin pseudogene 1

NBEAP3 Gene

neurobeachin pseudogene 3

NBEAP5 Gene

neurobeachin pseudogene 5

NBEAP6 Gene

neurobeachin pseudogene 6

NBEAP2 Gene

neurobeachin pseudogene 2

NBEAP4 Gene

neurobeachin pseudogene 4

NBEAL1 Gene

neurobeachin-like 1

NBEAL2 Gene

neurobeachin-like 2

The protein encoded by this gene contains a beige and Chediak-Higashi (BEACH) domain and multiple WD40 domains, and may play a role in megakaryocyte alpha-granule biogenesis. Mutations in this gene are a cause of gray platelet syndrome. [provided by RefSeq, Dec 2011]

nbea Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nbea in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NBEA Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NBEA from the Pathway Commons Protein-Protein Interactions dataset.

NBEAL1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NBEAL1 from the Pathway Commons Protein-Protein Interactions dataset.

NBEAL2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NBEAL2 from the Pathway Commons Protein-Protein Interactions dataset.