neurofilament, heavy polypeptide

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]


neurofilament, heavy polypeptide pseudogene 1

nefh Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefh in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NEFH Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NEFH from the Pathway Commons Protein-Protein Interactions dataset.