Name

NF2 Gene

neurofibromin 2 (merlin)

This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]

nf2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nf2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NF2 Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for NF2 from the MSigDB Cancer Gene Co-expression Modules dataset.

NF2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NF2 from the Pathway Commons Protein-Protein Interactions dataset.

nf2d9 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nf2d9 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL2777 (NF2) Gene Set

From NURSA Protein Complexes

proteins in the BL2777 (NF2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL2776 (NF2) Gene Set

From NURSA Protein Complexes

proteins in the BL2776 (NF2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

meningioma, nf2-related, somatic Gene Set

From OMIM Gene-Disease Associations

genes associated with the meningioma, nf2-related, somatic phenotype from the curated OMIM Gene-Disease Associations dataset.