Name

NHP2 Gene

NHP2 ribonucleoprotein

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

NHP2P2 Gene

NHP2 ribonucleoprotein pseudogene 2

NHP2P1 Gene

NHP2 ribonucleoprotein pseudogene 1

NHP2L1 Gene

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

nhp Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nhp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ribosomal protein L7Ae/L8/Nhp2 family Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribosomal protein L7Ae/L8/Nhp2 family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NHP2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NHP2 from the Pathway Commons Protein-Protein Interactions dataset.

NHP2L1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NHP2L1 from the Pathway Commons Protein-Protein Interactions dataset.