Name

NUBPL Gene

nucleotide binding protein-like

This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. Mutations in this gene cause mitochondrial complex I deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

NUBP2 Gene

nucleotide binding protein 2

This gene encodes an adenosine triphosphate (ATP) and metal-binding protein that is required for the assembly of cyotosolic iron-sulfur proteins. The encoded protein functions in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]

NUBP1 Gene

nucleotide binding protein 1

NUBP1 is a member of the NUBP/MRP subfamily of ATP-binding proteins (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]

NUB1 Gene

negative regulator of ubiquitin-like proteins 1

This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

nub Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nub in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nub1l Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nub1l in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nub1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nub1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NUBPL Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NUBPL from the Pathway Commons Protein-Protein Interactions dataset.

NUBP1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NUBP1 from the Pathway Commons Protein-Protein Interactions dataset.

NUB1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NUB1 from the Pathway Commons Protein-Protein Interactions dataset.

NUBP2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NUBP2 from the Pathway Commons Protein-Protein Interactions dataset.