NUF2 Gene

NUF2, NDC80 kinetochore complex component

This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]

nuf2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nuf2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NUF2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NUF2 from the Pathway Commons Protein-Protein Interactions dataset.

Kinetochore protein Nuf2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Kinetochore protein Nuf2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.