Name |
---|
|
|
|
|
positive
|
negative
|
positive
|
positive
|
positive
|
positive
|
negative
|
|
|
positive
|
positive
|
positive
|
negative
|
|
|
interferon
|
Interferon
|
Interferon
|
|
cd4-positive, cd25-positive, alpha-beta
|
|
CD4-positive, CD25-positive, alpha-beta
|
|
CD4-positive, CD25-positive, alpha-beta
|
cerebellar purkinje cell-granule cell precursor cell signaling involved in
|
cerebellar Purkinje cell-granule cell precursor cell signaling involved in
|
negative
|
|
negative
|
positive
|
|
rna polymerase ii transcription
|
rna polymerase ii transcription
|
|
negative
|
negative
|
positive
|
|
positive
|
|
|
|
negative
|
|
positive
|
negative
|
positive
|
|
|
negative
|
|
|
cd4-positive, cd25-positive, alpha-beta
|
Cell cycle
|
abnormal cd4-positive, cd25-positive, alpha-beta
|
abnormal cd4-positive, cd25-positive, alpha-beta
|
increased
|
decreased cd4-positive, cd25-positive, alpha-beta
|
decreased
|
abnormal
|
abnormal
|
abnormal
|
increased cd4-positive, cd25-positive, alpha-beta
|
|
Lymph_Node-
|
Skin-
|
Spleen-
|
Thymus-naive
|
CD4-positive, CD25-positive, alpha-beta
|
increased
|
abnormal CD4-positive, CD25-positive, alpha-beta
|
abnormal
|
decreased
|
decreased CD4-positive, CD25-positive, alpha-beta
|
abnormal
|
abnormal
|
increased CD4-positive, CD25-positive, alpha-beta
|
increased memory CD4-positive, CD25-positive, alpha-beta
|
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta
|
decreased memory CD4-positive, CD25-positive, alpha-beta
|
abnormal CD4-positive, CD25-positive, alpha-beta
|
increased CD4-positive, CD25-positive, alpha-beta
|
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta
|
increased
|
decreased
|
increased memory CD4-positive, CD25-positive, alpha-beta
|
decreased CD4-positive, CD25-positive, alpha-beta
|
decreased memory CD4-positive, CD25-positive, alpha-beta
|
Eomesodermin homolog(EOMES)+
|
Eomesodermin homolog(EOMES)+
|
|
Spleen_CT1_T Follicular
|
Spleen_CT1_T
|
Lymph node_CT1_T Follicular
|
Lymph node_CT1_T
|
Lymph node_CT1_T Follicular
|
Lymph node_CT1_T
|
Spleen_CT1_T Follicular
|
Spleen_CT1_T
|
CD4-positive, CD25-positive, alpha-beta
|
|
|
|
|
|
|
negative
|
|
positive
|
positive
|
negative
|
negative
|
positive
|
positive
|
|
|
|
|
|
negative
|
|
positive
|
|
|
negative
|
positive
|
|
negative
|
|
negative
|
negative
|
negative
|
|
|
|
negative
|
|
negative
|
|
positive
|
positive
|
positive
|
negative
|
positive
|
|
positive
|
negative
|
|
negative
|
negative
|
positive
|
negative
|
|
|
negative
|
negative
|
positive
|
positive
|
|
positive
|
|
negative
|
|
positive
|
positive
|
positive
|
positive
|
|
positive
|
negative
|
negative
|
negative
|
|
|
positive
|
positive
|
|
negative
|
|
negative
|
negative
|
|
negative
|
|
negative
|
positive
|
|
positive
|
|
|
|
negative
|
negative
|
negative
|
negative
|
positive
|
positive
|
|
|
positive
|
|
positive
|
negative
|
|
negative
|
positive
|
negative
|
positive
|
positive
|
negative
|
negative
|
positive
|
|
positive
|
negative
|
positive
|
|
positive
|
positive
|
positive
|
negative
|
positive
|
positive
|
positive
|
positive
|
|
|
|
positive
|
|
|
positive
|
negative
|
|
negative
|
|
|
negative
|
|
positive
|
|
positive
|
positive
|
positive
|
positive
|
negative
|
|
positive
|
negative
|
|
negative
|
|
positive
|
positive
|
|
negative
|
negative
|
negative
|
positive
|
|
|
positive
|
negative
|
positive
|
|
|
negative
|
positive
|
negative
|
|
positive
|
|
negative
|
positive
|
negative
|
positive
|
positive
|
positive
|
negative
|
positive
|
negative
|
negative
|
negative
|
negative
|
positive
|
positive
|
negative
|
negative
|
|
negative
|
positive
|
negative
|
positive
|
positive
|
|
positive
|
positive
|
positive
|
positive
|
positive
|
|
positive
|
negative
|
positive
|
positive
|
positive
|
negative
|
positive
|
negative
|
positive
|
|
|
|
|
|
negative
|
negative
|
negative
|
|
positive
|
positive
|
|
positive
|
positive
|
|
negative
|
|
negative
|
|
positive
|
|
positive
|
negative
|
negative
|
|
positive
|
positive
|
positive
|
negative
|
|
negative
|
negative
|
positive
|
positive
|
positive
|
|
negative
|
|
negative
|
|
|
|
positive
|
negative
|
|
positive
|
positive
|
negative
|
|
|
|
positive
|
negative
|
|
negative
|
positive
|
negative
|
positive
|
positive
|
|
|
positive
|
negative
|
|
negative
|
negative
|
|
negative
|
negative
|
|
positive
|
positive
|
positive
|
positive
|
positive
|
positive
|
negative
|
negative
|
positive
|
negative
|
negative
|
positive
|
negative
|
positive
|
negative
|
negative
|
|
negative
|
negative
|
|
negative
|
positive
|
|
negative
|
|
negative
|
positive
|
negative
|
positive
|
negative
|
negative
|
|
positive
|
|
negative
|
negative
|
negative
|
|
|
positive
|
positive
|
positive
|
|
|
negative
|
|
|
|
positive
|
|
|
positive
|
|
|
|
negative
|
|
|
negative
|
|
positive
|
|
positive
|
|
|
negative
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
positive
|
positive
|
positive
|
negative
|
positive
|
negative
|
positive
|
positive
|
negative
|
negative
|
negative
|
positive
|
positive
|
negative
|
negative
|
|
negative
|
positive
|
negative
|
positive
|
positive
|
|
positive
|
positive
|
positive
|
positive
|
positive
|
|
positive
|
negative
|
positive
|
positive
|
|
negative
|
positive
|
negative
|
positive
|
|
|
|
|
|
negative
|
negative
|
negative
|
|
positive
|
positive
|
|
positive
|
positive
|
negative
|
|
negative
|
|
positive
|
|
positive
|
negative
|
negative
|
|
positive
|
positive
|
positive
|
negative
|
|
negative
|
negative
|
positive
|
positive
|
positive
|
|
negative
|
|
negative
|
|
|
|
positive
|
negative
|
|
positive
|
positive
|
negative
|
|
|
|
positive
|
negative
|
|
negative
|
positive
|
negative
|
positive
|
positive
|
|
|
positive
|
negative
|
|
negative
|
negative
|
|
negative
|
negative
|
|
positive
|
positive
|
positive
|
positive
|
negative
|
positive
|
positive
|
negative
|
positive
|
negative
|
negative
|
positive
|
negative
|
positive
|
negative
|
negative
|
|
negative
|
negative
|
|
negative
|
positive
|
|
negative
|
|
negative
|
positive
|
negative
|
positive
|
negative
|
negative
|
|
positive
|
positive
|
|
negative
|
negative
|
|
|
positive
|
|
positive
|
|
|
negative
|
|
|
|
positive
|
|
|
positive
|
|
|
|
negative
|
positive
|
|
|
negative
|
|
positive
|
|
|
|
negative
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
adenocarcinoma; carcinoma, large cell; carcinoma, small cell; carcinoma, squamous cell; lung neoplasms; neoplasm
|
inner cell mass cell differentiation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the inner cell mass cell differentiation biological process from the curated GO Biological Process Annotations 2015 dataset. |
inner cell mass cell differentiation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the inner cell mass cell differentiation biological process from the curated GO Biological Process Annotations 2023 dataset. |
inner cell mass cell differentiation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the inner cell mass cell differentiation biological process from the curated GO Biological Process Annotations 2025 dataset. |
cdc25 and chk1
|
proteasome
|
proteasome
|
proteasome
|
proteasome
|
interferon
|
interferon
|
Emerin
|
Iron-
|
iron-
|
|
FOXP3_ABLATION_GDS2525_64_mouse_mature
|
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-
|
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-
|
proteasome
|
sterol
|
proteasome
|
proteasome
|
proteasome
|
rna polymerase iii
|
rna polymerase i
|
transcription
|
rna polymerase ii
|
intronic transcription
|
rna polymerase i
|
protein kinase a
|
sequence-specific transcription
|
|
rna polymerase ii
|
rna polymerase ii intronic transcription
|
|
transcription
|
phosphatidylinositol 3-kinase
|
intronic transcription
|
cytoskeletal
|
purine-rich negative
|
Protein phosphatase 4 core
|
Protein phosphatase 1,
|
KAT8
|
Steroidogenic acute
|
Protein phosphatase 1
|
Carboxypeptidase,
|
Ribosomal biogenesis
|
26S proteasome,
|
KAT8
|
Myelin gene
|
Myelin gene
|
Casein kinase II,
|
KAT8
|
Cyclin-dependent kinase,
|
Metal
|
Dolichol phosphate-mannose biosynthesis
|
26S proteasome
|
Ion channel
|
26S proteasome non-ATPase
|
Protein phosphatase 1
|
GTP cyclohydrolase I, feedback
|
|
Phosphoinositide 3-kinase
|
Rab3-GAP
|
Iron
|
Protein phosphatase 2A,
|
Aspartate carbamoyltransferase
|
Interferon
|
Immunodeficiency virus transactivating
|
Protein phosphatase 2A,
|
Protein phosphatase 1
|
V-type ATP synthase
|
Carboxypeptidase-like,
|
PI3 kinase, P85
|
Protein phosphatase 1
|
|
26S proteasome
|
Interferon
|
Sterol
|
Myelin gene
|
Dimerization-anchoring domain
|
26S proteasome non-ATPase
|
cAMP-dependent protein kinase
|
Interferon
|
Protein phosphatase 1
|
Nitrogen
|
Interferon
|
Nuclear envelope phosphatase-
|
|
Iron
|
Casein kinase II,
|
Histidine-tRNA ligase/ATP phosphoribosyltransferase
|
Na(+)/H(+) exchange
|
Poly(ADP-ribose) polymerase,
|
Aconitate/iron
|
Protein phosphatase 1,
|
Protein phosphatase 2A,
|
Rab3GAP
|
Steroidogenic acute
|
Interferon
|
Putative phosphatase
|
Glucokinase
|
26S proteasome
|
Interferon
|
Casein kinase II,
|
Adipose-
|
Dynein
|
absent
|
Glucocorticoid receptor
|
|
Signal
|
|
Ptf1a related
|
Gene
|
Steroidogenic Acute
|
Elevated Proportion
|
Reduced Proportion
|
proteasome
|
|
|
RNA polymerase II cis-
|
cis-
|
transcription cis-
|
RNA polymerase II transcription
|
protein kinase A
|
RNA polymerase I cis-
|
RNA polymerase III transcription
|
purine-rich negative
|
intronic transcription
|
RNA polymerase II intronic transcription
|
|
phosphatidylinositol 3-kinase
|
transcription
|
cytoskeletal
|
|
RNA polymerase I transcription
|
RNA polymerase III cis-
|
absent
|
Human - PBMC - L2 -
|
Human - PBMC - L3 - Memory
|
Human - PBMC - L3 - Naive
|
|
|
|
|
|
Foxp3+
|
|
|
CD4+CD25+
|
Effector
|
Induced
|
Naive
|
Natural
|
|
|
Induced
|
|
FOXP3+ natural
|
Natural
|
|
Induced
|
|
Memory
|
Activated
|
|
|
Activated CD25+
|
|
|
|
TolDC-induced
|
Natural
|
|
Ovalbumin-specific
|
Tumor
|
|
|
Effector
|
|
|
|
Follicular
|
|
|
|
|
|
|
Memory
|
|
|
|
|
|
|
B10
|
GrB+
|
|
|
|
|
|
|
Effector
|
|
|
|
|
|
|
|
|
GrB+
|
IgA+
|
|
Effector
|
|
|
|
|
|
Follicular
|
CD4 peripherally derived
|
|
|
|
|
|
|
|
|
|
|
TIM-1+
|
PD-1hi
|
Suppressive
|
Resting
|
|
|
|
|
|
Tumor-infiltrating
|
|
|
|
|
CD4+CD25+
|
|
|
|
|
|
|
|
|
GrB+
|
|
|
|
|
|
|
|
|
GrB+
|
|
|
|
|
|
T2-MZP
|
PD-L1+
|
CD4+CD25+
|
|
|
|
|
Activated
|
|
B10
|
|
Thymus-derived
|
|
|
|
|
|
|
|
|
|
Effector
|
|
|
Central memory
|
|
B10
|
GrB+
|
|
|
Sterol
|
Gene
|
DDX1 as a
|
Angiopoietin like protein 8
|
PTF1A related
|
|
TROP2
|
RUNX1 and FOXP3 control the development
|
SARS-CoV-1 targets host intracellular signalling and
|
SARS-CoV-2 targets host intracellular signalling and
|
Signal
|
Blood_CT2_T
|
Bone marrow_CT2_T
|
Blood_CT2_T
|
Bone marrow_CT2_T
|
proteasome
|
|
|
|
|
|
RNA polymerase II cis-
|
cis-
|
transcription cis-
|
RNA polymerase II transcription
|
protein kinase A
|
RNA polymerase I cis-
|
RNA polymerase III transcription
|
purine-rich negative
|
intronic transcription
|
RNA polymerase I transcription
|
RNA polymerase II intronic transcription
|
|
phosphatidylinositol 3-kinase
|
cytoskeletal
|
|
RNA polymerase III cis-
|
|
Proteasome
|
Proteasome
|
Proteasome
|
Interferon
|
Interferon
|
Interferon
|
Proteasome
|
Proteasome
|
Kelch-containing formin
|
Actin cytoskeleton-
|
Proteasome
|
Interferon
|
negative
|