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ABL2 GeneABL proto-oncogene 2, non-receptor tyrosine kinase This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009] |
abl2 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term abl2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
ABL2 Gene SetFrom KEA Substrates of Kinases substrates of the kinase ABL2 from the curated KEA Substrates of Kinases dataset. |
ABL2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for ABL2 from the Pathway Commons Protein-Protein Interactions dataset. |
ABL2 Gene SetFrom PhosphoSitePlus Substrates of Kinases substrates of the kinase ABL2 from the curated PhosphoSitePlus Substrates of Kinases dataset. |
ABL2-HRAS-RIN1 complex Gene Setproteins in the ABL2-HRAS-RIN1 complex protein complex from the CORUM Protein Complexes dataset. |
abl2arg Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term abl2arg in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
BL1045 (ABL2) Gene Setproteins in the BL1045 (ABL2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |