Name

ACHE Gene

acetylcholinesterase (Yt blood group)

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]

ache Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ache in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ACHE Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ACHE from the Pathway Commons Protein-Protein Interactions dataset.

Acheiropodia Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Acheiropodia from the curated CTD Gene-Disease Associations dataset.

acheiropody Gene Set

From DISEASES Text-mining Gene-Disease Assocation Evidence Scores

genes co-occuring with the disease acheiropody in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

ache, low back; low back pain Gene Set

From GAD Gene-Disease Associations

genes associated with the disease ache, low back; low back pain in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

ache, low back; intervertebral disk displacement; spinal osteophytosis Gene Set

From GAD Gene-Disease Associations

genes associated with the disease ache, low back; intervertebral disk displacement; spinal osteophytosis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

ache, low back; low back pain; scoliosis; spinal diseases Gene Set

From GAD Gene-Disease Associations

genes associated with the disease ache, low back; low back pain; scoliosis; spinal diseases in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

ache, low back; arthritis, psoriatic; inflammatory bowel disease, nos; inflammatory bowel diseases; low back pain; psoriatic arthropathy; rheumatoid spondylitis; spondylarthropathies; spondylitis, ankylosing Gene Set

From GAD Gene-Disease Associations

genes associated with the disease ache, low back; arthritis, psoriatic; inflammatory bowel disease, nos; inflammatory bowel diseases; low back pain; psoriatic arthropathy; rheumatoid spondylitis; spondylarthropathies; spondylitis, ankylosing in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

ache, low back; acute disease; low back pain; pain; sciatica Gene Set

From GAD Gene-Disease Associations

genes associated with the disease ache, low back; acute disease; low back pain; pain; sciatica in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

ache, low back; intervertebral disk displacement; low back pain; occupational diseases Gene Set

From GAD Gene-Disease Associations

genes associated with the disease ache, low back; intervertebral disk displacement; low back pain; occupational diseases in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

ache, low back; intervertebral disk displacement; low back pain Gene Set

From GAD Gene-Disease Associations

genes associated with the disease ache, low back; intervertebral disk displacement; low back pain in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

ache, low back; intervertebral disk degeneration; low back pain Gene Set

From GAD Gene-Disease Associations

genes associated with the disease ache, low back; intervertebral disk degeneration; low back pain in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

achebuche Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term achebuche in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

acheron Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term acheron in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

acher Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term acher in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

aches Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term aches in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

achet Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term achet in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ACHE_OE_GDS891_241_mouse_Prefrontal cortex Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the ACHE_OE_GDS891_241_mouse_Prefrontal cortex gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

acheiropody Gene Set

From OMIM Gene-Disease Associations

genes associated with the acheiropody phenotype from the curated OMIM Gene-Disease Associations dataset.

achene Gene Set

From TISSUES Text-mining Tissue Protein Expression Evidence Scores

proteins co-occuring with the tissue achene in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.