Name

ACSL3 Gene

acyl-CoA synthetase long-chain family member 3

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

acsl3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term acsl3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ACSL3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ACSL3 from the Pathway Commons Protein-Protein Interactions dataset.

acsl35 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term acsl35 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.