Name

AIRE Gene

autoimmune regulator

This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]

aire Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term aire in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

AIRE Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for AIRE from the Pathway Commons Protein-Protein Interactions dataset.

AIRE homodimer complex Gene Set

From CORUM Protein Complexes

proteins in the AIRE homodimer complex protein complex from the CORUM Protein Complexes dataset.

aireregulated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term aireregulated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

airephd1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term airephd1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

airemediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term airemediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

aires Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term aires in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

aireexpressing Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term aireexpressing in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

aireinduced Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term aireinduced in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

airesistant Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term airesistant in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

airep63 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term airep63 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

AIRE_KO_GDS2015_33_mouse_thymic epithelial cells Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the AIRE_KO_GDS2015_33_mouse_thymic epithelial cells gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

AIRE_KO_GDS2274_245_mouse_Medullary thymic epithelial cells (with low CD80 expression) Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the AIRE_KO_GDS2274_245_mouse_Medullary thymic epithelial cells (with low CD80 expression) gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression) Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression) gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

aire_21746930_treg_cd8pos_cd28low_lof_mouse_gpl6246_gds4373 Gene Set

From GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations

genes differentially expressed following the aire_21746930_treg_cd8pos_cd28low_lof_mouse_gpl6246_gds4373 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

Autoimmune regulator, AIRE Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Autoimmune regulator, AIRE protein domain from the InterPro Predicted Protein Domain Annotations dataset.