Name

AKT2 Gene

v-akt murine thymoma viral oncogene homolog 2

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]

akt2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term akt2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

AKT2 Gene Set

From KEA Substrates of Kinases

substrates of the kinase AKT2 from the curated KEA Substrates of Kinases dataset.

AKT2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for AKT2 from the Pathway Commons Protein-Protein Interactions dataset.

AKT2 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase AKT2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

POSH-AKT2 complex Gene Set

From CORUM Protein Complexes

proteins in the POSH-AKT2 complex protein complex from the CORUM Protein Complexes dataset.

TCL1(trimer)-AKT2 complex Gene Set

From CORUM Protein Complexes

proteins in the TCL1(trimer)-AKT2 complex protein complex from the CORUM Protein Complexes dataset.

akt2b23 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term akt2b23 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

akt2dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term akt2dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

akt2foxo3a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term akt2foxo3a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

AKT2_knockdown_44_GSE12291 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the AKT2_knockdown_44_GSE12291 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

AKT2_knockout_221_GSE19079 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the AKT2_knockout_221_GSE19079 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

BL2164 (AKT2) Gene Set

From NURSA Protein Complexes

proteins in the BL2164 (AKT2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.