Name

ALG8 Gene

ALG8, alpha-1,3-glucosyltransferase

This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

ALG8 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ALG8 from the Pathway Commons Protein-Protein Interactions dataset.

Defective ALG8 causes ALG8-CDG (CDG-1h) Gene Set

From Reactome Pathways

proteins participating in the Defective ALG8 causes ALG8-CDG (CDG-1h) pathway from the Reactome Pathways dataset.

Glycosyl transferase, ALG6/ALG8 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glycosyl transferase, ALG6/ALG8 protein domain from the InterPro Predicted Protein Domain Annotations dataset.