AP2M1 Gene

adaptor-related protein complex 2, mu 1 subunit

This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

AP2M1 Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for AP2M1 from the MSigDB Cancer Gene Co-expression Modules dataset.

AP2M1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for AP2M1 from the Pathway Commons Protein-Protein Interactions dataset.