Name

ARHGEF1 Gene

Rho guanine nucleotide exchange factor (GEF) 1

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

ARHGEF19-AS1 Gene

ARHGEF19 antisense RNA 1

ARHGEF10L Gene

Rho guanine nucleotide exchange factor (GEF) 10-like

ARHGEF10L is a member of the RhoGEF family of guanine nucleotide exchange factors (GEFs) that activate Rho GTPases (Winkler et al., 2005 [PubMed 16112081]).[supplied by OMIM, Dec 2008]

ARHGEF10 Gene

Rho guanine nucleotide exchange factor (GEF) 10

This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

ARHGEF11 Gene

Rho guanine nucleotide exchange factor (GEF) 11

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

ARHGEF12 Gene

Rho guanine nucleotide exchange factor (GEF) 12

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

ARHGEF15 Gene

Rho guanine nucleotide exchange factor (GEF) 15

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene. [provided by RefSeq, Aug 2010]

ARHGEF16 Gene

Rho guanine nucleotide exchange factor (GEF) 16

Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions. [provided by RefSeq, Jul 2008]

ARHGEF17 Gene

Rho guanine nucleotide exchange factor (GEF) 17

ARHGEF18 Gene

Rho/Rac guanine nucleotide exchange factor (GEF) 18

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

ARHGEF19 Gene

Rho guanine nucleotide exchange factor (GEF) 19

Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008]

arhgef1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term arhgef1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ARHGEF1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF1 from the Pathway Commons Protein-Protein Interactions dataset.

arhgef12 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term arhgef12 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

arhgef15 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term arhgef15 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

arhgef16 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term arhgef16 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL7844 (ARHGEF16) Gene Set

From NURSA Protein Complexes

proteins in the BL7844 (ARHGEF16) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL7841 (ARHGEF12) Gene Set

From NURSA Protein Complexes

proteins in the BL7841 (ARHGEF12) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL7814 (ARHGEF11) Gene Set

From NURSA Protein Complexes

proteins in the BL7814 (ARHGEF11) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

ARHGEF12 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for ARHGEF12 from the NURSA Protein-Protein Interactions dataset.

ARHGEF18 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for ARHGEF18 from the NURSA Protein-Protein Interactions dataset.

ARHGEF10 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for ARHGEF10 from the NURSA Protein-Protein Interactions dataset.

ARHGEF10L Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF10L from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF10 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF10 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF11 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF11 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF12 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF12 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF15 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF15 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF16 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF16 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF17 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF17 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF18 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF18 from the Pathway Commons Protein-Protein Interactions dataset.

ARHGEF19 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARHGEF19 from the Pathway Commons Protein-Protein Interactions dataset.