actin related protein 2/3 complex, subunit 1B, 41kDa

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011]

arpc1b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term arpc1b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ARPC1B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ARPC1B from the Pathway Commons Protein-Protein Interactions dataset.