Name

ATF1 Gene

activating transcription factor 1

This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]

ATF1P1 Gene

activating transcription factor 1 pseudogene 1

ATF1 Gene Set

From ENCODE Transcription Factor Targets

target genes of the ATF1 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

atf1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term atf1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ATF1 Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the ATF1 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

ATF1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ATF1 from the Pathway Commons Protein-Protein Interactions dataset.

ATF1 Gene Set

From TRANSFAC Curated Transcription Factor Targets

target genes of the ATF1 transcription factor in low- or high-throughput transcription factor functional studies from the TRANSFAC Curated Transcription Factor Targets dataset.

ATF1 Gene Set

From TRANSFAC Predicted Transcription Factor Targets

target genes of the ATF1 transcription factor predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.

ATF1_K562_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the ATF1_K562_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

atf1and Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term atf1and in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

atf1-atf4 transcription factor complex Gene Set

From GO Cellular Component Annotations

proteins localized to the atf1-atf4 transcription factor complex cellular component from the curated GO Cellular Component Annotations dataset.

cAMP-dependent transcription factor ATF1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the cAMP-dependent transcription factor ATF1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

SC-28673 (ATF1) Gene Set

From NURSA Protein Complexes

proteins in the SC-28673 (ATF1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.