ATP1B1 Gene

ATPase, Na+/K+ transporting, beta 1 polypeptide

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]

ATP1B1P1 Gene

ATPase, Na+/K+ transporting, beta 1 polypeptide pseudogene 1

atp1b1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term atp1b1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ATP1B1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ATP1B1 from the Pathway Commons Protein-Protein Interactions dataset.