ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
ATP6V0B Gene Set
interacting proteins for ATP6V0B from the Pathway Commons Protein-Protein Interactions dataset.