Name

ATP6V1E1 Gene

ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome. [provided by RefSeq, Jul 2008]

ATP6V1E1P2 Gene

ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 pseudogene 2

ATP6V1E1P1 Gene

ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 pseudogene 1

ATP6V1E1P3 Gene

ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 pseudogene 3

atp6v1e1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term atp6v1e1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ATP6V1E1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ATP6V1E1 from the Pathway Commons Protein-Protein Interactions dataset.