Name

BAK1 Gene

BCL2-antagonist/killer 1

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]

BAK1P1 Gene

BCL2-antagonist/killer 1 pseudogene 1

BAK1P2 Gene

BCL2-antagonist/killer 1 pseudogene 2

bak1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bak1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BAK1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for BAK1 from the Pathway Commons Protein-Protein Interactions dataset.

MCL1-BAK1 complex Gene Set

From CORUM Protein Complexes

proteins in the MCL1-BAK1 complex protein complex from the CORUM Protein Complexes dataset.

Tp53-BAK1 complex Gene Set

From CORUM Protein Complexes

proteins in the Tp53-BAK1 complex protein complex from the CORUM Protein Complexes dataset.

tBID-BAK1 complex Gene Set

From CORUM Protein Complexes

proteins in the tBID-BAK1 complex protein complex from the CORUM Protein Complexes dataset.